Is Arthropod Saliva the Achilles’ Heel of Vector-Borne Diseases?
نویسندگان
چکیده
منابع مشابه
Is Arthropod Saliva the Achilles’ Heel of Vector-Borne Diseases?
establishment of a vector-borne disease. For example, tick-derived saliva factors appear to inhibit inflammatory cytokine secretion thus preventing efficient immune responses against tick-borne Rickettsia (4); a defined molecule in the saliva of the Aedes aegypti mosquito (SAAG-4) has the potential to alter the Th-profile of the bite-induced immune response likely rendering the host unable to e...
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The impact of the microbiota on the immune status of its host is a source of intense research and publicity. In comparison, the effect of arthropod microbiota on vector-borne infectious diseases has received little attention. A better understanding of the vector microbiota in relation to mammalian host immune responses is vital, as it can lead to strategies that affect transmission and improve ...
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1 Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06512, USA 2Department of Biological Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USA 3Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China 4 Institute of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soocho...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2013
ISSN: 1664-3224
DOI: 10.3389/fimmu.2013.00255